Synthesis and Characterization of Rhodamine B-ethylenediamine-hyaluronan Acid as Potential Biological Functional Materials

International Conference on Computer Information and Automation Engineering

计算机科学;运输工程

Li, Y.L.^1,2,3,4 ; Wang, W.X.^1,2,3,4 ; Wang, Y.^1,2,3,4 ; Zhang, W.B.^1,2,3,4 ; Gong, H.M.^1,2,3,4 ; Liu, M.X.^1,2,3,4

Key Laboratory of Fermentation Engineering, Ministry of Education, Hubei University of Technology, Wuhan

430068, China^1

Hubei Provincial Cooperative Innovation Center of Industrial Fermentation, Hubei University of Technology, Wuhan

430068, China^2

National 111 Center for Cellular Regulation and Molecular Pharmaceutics, Hubei University of Technology, Wuhan

430068, China^3

Hubei Key Laboratory of Industrial Microbiology, Hubei University of Technology, Wuhan

430068, China^4

关键词: Amidation reaction;    Ammonolysis reactions;    Drug delivery system;    Ethylene diamine;    Fluorescent polymers;    Fourier transform infra red (FTIR) spectroscopy;    Synthesis and characterizations;    UV-Vis spectrometry;   

Others  :  https://iopscience.iop.org/article/10.1088/1757-899X/359/1/012040/pdf
DOI  :  10.1088/1757-899X/359/1/012040

学科分类：计算机科学（综合）

来源: IOP

【 摘 要 】

The purpose of this study is to synthesize and characterize fluorescent polymers, rhodamine B-ethylenediamine-hyaluronan acid (RhB-EA-HA). RhB-EA-HA was successfully synthesized by ester ammonolysis reaction and amidation reaction. Moreover, the structural properties of RhB-EA-HA were characterized by 1H-NMR spectra, UV-vis spectrometry and Fourier transform infrared spectroscopy (FT-IR). RhB-EA-HA can be grafted on the surface of silica nanomaterials, which may be potential biological functional materials for drug delivery system.