Potential anti-Dengue Concoction of Carica Papaya (C. Papaya) Leaf and G. Mangostana (G. Mangostana) Pericarp and Their Bioactivity Enhancement by Fermentation: A Review

3rd International Conference on Global Sustainability and Chemical Engineering

工业技术;化学工业

So'Aib, M.S.^1 ; Salihon, J.^1 ; Tan, H.L.^1

Faculty of Chemical Engineering, Universiti Teknologi MARA, Shah Alam

40450, Malaysia^1

关键词: Anti-inflammatories;    Anti-viral effects;    Carica papaya;    Fermented foods;    Immunomodulatory;    Microbiome;    Polyphenolic content;    Polyphenols;   

Others  :  https://iopscience.iop.org/article/10.1088/1757-899X/358/1/012036/pdf
DOI  :  10.1088/1757-899X/358/1/012036

学科分类：工业工程学

来源: IOP

【 摘 要 】

This review highlights the anti-dengue potency of Carica Papaya leaf (CPL) extract which was associated with platelet increase and other medicinal properties such as antiinflammatory and antioxidant. Garcinia Mangostana's pericarp (GMP) extract have much commonalities with CPL, in addition to antiviral and immunomodulatory properties of the former. These properties may exhibit, yet unproven, analgesic, hemorrhage prevention and antiviral effects that may facilitate dengue recovery. Nevertheless, the limited bioavailability of native polyphenolic contents of both, as hinted by studies on colonic microbiome metabolism on dietary polyphenols, highlighted fermentation as viable method to enhance the functionality of the compounds. Thus, this review also highlights some relevant parameters in existing fermentation of well known fermented foods that impact their bioactivity, functionality and palatability that may applicable for the development of CPL and GMP fermentations.