Synthesis of Calcium Phosphate Composite Organogels by Using Emulsion Method for Dentine Occlusion Materials

4th International Conference on Advanced Engineering and Technology

Nopteeranupharp, C.^1 ; Akkarachaneeyakorn, K.^1 ; Songsasaen, A.^1

Faculty of Science, Department of Chemistry, Kasetsart University, 50 Ngamwongwan street, Lat Yao, Chatuchak, Bangkok

10900, Thailand^1

关键词: Dentine slices;    Emulsion method;    Ethylene oxides;    Methods and materials;    Nano-droplets;    Osteoconductivity;    Propylene oxide;    Water in oil emulsions;   

Others  :  https://iopscience.iop.org/article/10.1088/1757-899X/317/1/012027/pdf
DOI  :  10.1088/1757-899X/317/1/012027

来源: IOP

【 摘 要 】

Dentinal hypersensitivity (DH) is one of the most human's problems caused by the erosion of enamel. There are many methods and materials to solve this problem. Calcium phosphate is an excellent alternative for curing this symptom because of its osteoconductivity, and biocompatibility properties. The low-cost and low-toxicity calcium phosphate nanogel was fabricated by using emulsion method and characterized by using TEM, EDX, and DLS techniques. The results showed that P123 (poly (ethylene oxide)19-block-Poly (propylene oxide)69-block-poly (ethylene oxide)19) has played a major role as template and gel formation, SDS was used as a surfactant to form water-in-oil emulsion nanodroplets with circle-like shape. Moreover, the ability of synthesised organogel to occlude the exposed dentine tubules was tested on the model of human's dentine slices. The results showed that calcium phosphate composite organogel can be efficiently occluded on dentine slice, characterized by SEM technique, after 1 day.