Application of Model Animals in the Study of Drug Toxicology

5th Annual International Conference on Material Science and Environmental Engineering

材料科学;生态环境科学

Song, Yagang^1 ; Miao, Mingsan^1

Department of Pharmacy, Henan University of Chinese Medicine, Zhengzhou, China^1

关键词: Body condition;    Drug research;    Drug safety;    Key factors;    Model animals;    Toxicology tests;   

Others  :  https://iopscience.iop.org/article/10.1088/1757-899X/301/1/012067/pdf
DOI  :  10.1088/1757-899X/301/1/012067

来源: IOP

【 摘 要 】

Drug safety is a key factor in drug research and development, Drug toxicology test is the main method to evaluate the safety of drugs, The body condition of an animal has important implications for the results of the study, Previous toxicological studies of drugs were carried out in normal animals in the past, There is a great deviation from the clinical practice.The purpose of this study is to investigate the necessity of model animals as a substitute for normal animals for toxicological studies, It is expected to provide exact guidance for future drug safety evaluation.