Recent advances in Optical Computed Tomography (OCT) imaging system for three dimensional (3D) radiotherapy dosimetry

International Nuclear Science, Technology and Engineering Conference 2017

原子能学

Abdul Rahman, Ahmad Taufek^1,2,3 ; Rosli, Nurul Farah^4 ; Zain, Shafirah Mohd^4 ; Zin, Hafiz M.^4

Faculty of Applied Sciences, Universiti Teknologi MARA, Selangor Shah Alam

40450, Malaysia^1

Institute of Science, Universiti Teknologi MARA, Selangor Shah Alam

40450, Malaysia^2

Departmet of Physics, University of Surrey, Guildford, Surrey

GU2 7XH, United Kingdom^3

Advanced Medical and Dental Institute, Universiti Sains Malaysia, Bertam, Pulau Pinang

13200, Malaysia^4

关键词: 3-D measurement;    Cancerous tissues;    CMOS image sensor;    Current detector;    Delivery techniques;    Healthy tissues;    Optical computed tomography;    Threedimensional (3-d);   

Others  :  https://iopscience.iop.org/article/10.1088/1757-899X/298/1/012036/pdf
DOI  :  10.1088/1757-899X/298/1/012036

来源: IOP

【 摘 要 】

Radiotherapy delivery techniques for cancer treatment are becoming more complex and highly focused, to enable accurate radiation dose delivery to the cancerous tissue and minimum dose to the healthy tissue adjacent to tumour. Instrument to verify the complex dose delivery in radiotherapy such as optical computed tomography (OCT) measures the dose from a three-dimensional (3D) radiochromic dosimeter to ensure the accuracy of the radiotherapy beam delivery to the patient. OCT measures the optical density in radiochromic material that changes predictably upon exposure to radiotherapy beams. OCT systems have been developed using a photodiode and charged coupled device (CCD) as the detector. The existing OCT imaging systems have limitation in terms of the accuracy and the speed of the measurement. Advances in on-pixel intelligence CMOS image sensor (CIS) will be exploited in this work to replace current detector in OCT imaging systems. CIS is capable of on-pixel signal processing at a very fast imaging speed (over several hundred images per second) that will allow improvement in the 3D measurement of the optical density. The paper will review 3D radiochromic dosimeters and OCT systems developed and discuss how CMOS based OCT imaging will provide accurate and fast optical density measurements in 3D. The paper will also discuss the configuration of the CMOS based OCT developed in this work and how it may improve the existing OCT system.