Flow behaviour in normal and Meniere's disease of endolymphatic fluid inside the inner ear

2nd International Conference on Computational Fluid Dynamics in Research and Industry

力学;计算机科学;工业技术

Sufyan Amir Paisal, Muhammad^1 ; Azmi Wahab, Muhamad^1 ; Taib, Ishkrizat^1 ; Mat Isa, Norasikin^1 ; Ramli, Yahaya^1 ; Md Seri, Suzairin^1 ; Darlis, Nofrizalidris^2 ; Osman, Kahar^3 ; Zahran Md Khudzari, Ahmad^3 ; Nordin, Normayati^1

Simulation and Turbulence Research Group, Faculty of Mechanical and Manufacturing Engineering, Universiti Tun Hussein Onn Malaysia, Parit Raja, Johor Batu Pahat

86400, Malaysia^1

Faculty of Engineering TechnologyUniversiti Tun Hussein Onn Malaysia, Parit Raja Johor Batu Pahat

86400, Malaysia^2

Faculty of Mechanical Engineering, Universiti Teknologi Malaysia, Skudai Johor

81310, Malaysia^3

关键词: Computer aided designs (CAD);    Constant flow rates;    Flow charac-teristics;    Flow recirculation;    Fluctuating pressures;    Meniere's disease;    Three-dimensional model;    Vestibular system;   

Others  :  https://iopscience.iop.org/article/10.1088/1757-899X/243/1/012033/pdf
DOI  :  10.1088/1757-899X/243/1/012033

来源: IOP

【 摘 要 】

Meniere's disease is a rare disorder that affects the inner ear which might be more severe if not treated. This is due to fluctuating pressure of the fluid in the endolymphatic sac and dysfunction of cochlea which causing the stretching of vestibular membrane. However, the pattern of the flow recirculation in endolymphatic region is still not fully understood. Thus, this study aims to investigate the correlation between the increasing volume of endolymphatic fluid and flow characteristics such as velocity, pressure and wall shear stress. Three dimensional model of simplified endolymphatic region is modeled using computer aided design (CAD) software and simulated using computational fluid dynamic (CFD) software. There are three different models are investigated; normal (N) model, Meniere's disease model with less severity (M1) and Meniere's disease model with high severity (M2). From the observed, the pressure drop between inlet and outlet of inner ear becomes decreases as the outlet pressure along with endolymphatic volume increases. However, constant flow rate imposed at the inlet of endolymphatic showing the lowest velocity. Flow recirculation near to endolymphatic region is occurred as the volume in endolympathic increases. Overall, high velocity is monitored near to cochlear duct, ductus reuniens and endolymphatic duct. Hence, these areas show high distributions of wall shear stress (WSS) that indicating a high probability of endolymphatic wall membrane dilation. Thus, more severe conditions of Meniere's disease, more complex of flow characteristic is occurred. This phenomenon presenting high probability of rupture is predicted at the certain area in the anatomy of vestibular system.