Computational fluid dynamics simulation of pressure and velocity distribution inside Meniere's diseased vestibular system

2nd International Conference on Computational Fluid Dynamics in Research and Industry

力学;计算机科学;工业技术

Shamsuddin, N.F.H.^1 ; Isa, N.M.^1 ; Taib, I.^2 ; Mohammed, A.N.^2

Energy and Technologies Research Group (EnRG), Department of Thermofluid Engineering, Faculty of Mechanical and Manufacturing Engineering, UniversitiTun Hussein Onn Malaysia (UTHM), Malaysia^1

Simulation and Turbulence Research Group (FAST), Universiti Tun Hussien Onn Malaysia (UTHM), Malaysia^2

关键词: Commercial software;    Computational fluid dynamics methods;    Computational fluid dynamics simulations;    Magnetic resonance images (MRI);    Meniere's disease;    Pressure and velocity distributions;    Three dimensional geometry;    Velocity profiles;   

Others  :  https://iopscience.iop.org/article/10.1088/1757-899X/243/1/012041/pdf
DOI  :  10.1088/1757-899X/243/1/012041

来源: IOP

【 摘 要 】

Meniere's disease or known as endolymphatic hydrops is an incurable vestibular disorder of the inner ear. This is due to the excessive fluid build-up in the endolymphatic sac which causing the vestibular endolymphatic membrane to start stretching. Although this mechanism has been widely accepted as the likely mechanism of Meniere's syndrome, the reason for its occurrence remains unclear. Thus, the aims of this study to investigate the critical parameters of fluid flow in membranous labyrinth that is influencing instability of vestibular system. In addition, to visualise the flow behaviour between a normal membranous labyrinth and dilated membranous labyrinth in Meniere's disease in predicting instability of vestibular system. Three dimensional geometry of endolymphatic sac is obtained from Magnetic Resonance Images (MRI) and reconstructed using commercial software. As basis of comparison the two different model of endolymphatic sac is considered in this study which are normal membranous labyrinth for model I and dilated membranous labyrinth for model II. Computational fluid dynamics (CFD) method is used to analyse the behaviour of pressure and velocity flow in the endolymphatic sac. The comparison was made in terms of pressure distribution and velocity profile. The results show that the pressure for dilated membranous labyrinth is greater than normal membranous labyrinth. Due to abnormally pressure in the vestibular system, it leads to the increasing value of the velocity at dilated membranous labyrinth while at the normal membranous labyrinth the velocity values decreasing. As a conclusion by changing the parameters which is pressure and velocity can significantly affect to the instability of vestibular system for Meniere's disease.