The Effects of Micromixing Two Solutions of Two Concentrations in a Two Tier PDMS Micromixer

International Research and Innovation Summit 2017

Sundra, Sargunan^1 ; Soon, Chin Fhong^1 ; Zainal, Nurfarina^1 ; Tee, Kian Sek^1 ; Ahmad, Nornabihah^1 ; Gan, Siew Hua^2

Biosensor and Bioengineering Laboratory, MiNT-SRC, Faculty of Electric and Electronic Engineering, Universiti Tun Hussein Onn Malaysia, Parit Raja, Johor, Batu Pahat

86400, Malaysia^1

Human Genome Centre, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian, Kota Bharu Kelantan

16150, Malaysia^2

关键词: Biological applications;    Concentrated liquids;    Diffusion theory;    Distilled water;    Dye solutions;    Integrated microfluidic systems;    Mixing performance;    Polydimethylsiloxane PDMS;   

Others  :  https://iopscience.iop.org/article/10.1088/1757-899X/226/1/012121/pdf
DOI  :  10.1088/1757-899X/226/1/012121

来源: IOP

【 摘 要 】

Micromixing technology has drastically advanced in the past few decades. Micromixers are one of the elements in integrated microfluidic systems for chemical, analytical chemistry, pharmaceutical, and biological applications. In this study, two tier micromixer was used to mix and dilute two solutions of similar and different concentration in order to investigate performance of micromixer's mixing. This paper presents the fabrication of a designed micromixer using polydimethylsiloxane (PDMS) and vinyl tape methods which reduce time, cost and complexity of prototyping. The serpentine structure of the microchannels was designed to enhance both mixing and dilution. Two types of food dyes and distilled water were used to investigate the mixing performance of the micromixer followed by spectrophotometry analysis. It is observed that the single dye solution and distilled water shows better mixing performance compared to the micromixing of two dye solutions which was supported by the diffusion theory. 2.00 ml/min was the optimum flow rate that allow optimum mixing and dilution between two different concentrated liquids.