Investigation of spatial resolution dependent variability in transcutaneous oxygen saturation using point spectroscopy system

International Research and Innovation Summit 2017

Philimon, Sheena P.^1 ; Huong, Audrey K. C.^1 ; Ngu, Xavier T. I.^1

Faculty of Electrical and Electronic Engineering, Universiti Tun Hussein Onn Malaysia, Johor, Batu Pahat, Malaysia^1

关键词: Appropriate distances;    Extinction coefficients;    Iterative fitting procedures;    Oxygen saturation;    Sampling distance;    Spatial resolution;    Spectroscopic data;    Wavelength ranges;   

Others  :  https://iopscience.iop.org/article/10.1088/1757-899X/226/1/012122/pdf
DOI  :  10.1088/1757-899X/226/1/012122

来源: IOP

【 摘 要 】

This paper aims to investigate the variation in one's percent mean transcutaneous oxygen saturation (StO2) with differences in spatial resolution of data. This work required the knowledge of extinction coefficient of hemoglobin derivatives in the wavelength range of 520 - 600 nm to solve for the StO2value via an iterative fitting procedure. A pilot study was conducted on three healthy subjects with spectroscopic data collected from their right index finger at different arbitrarily selected distances. The StO2value estimated by Extended Modified Lambert Beer (EMLB) model revealed a higher mean StO2of 91.1 ± 1.3% at a proximity distance of 30 mm compared to 60.83 ± 2.8% at 200 mm. The results showed a high correlation between data spatial resolution and StO2value, and revealed a decrease in StO2value as the sampling distance increased. The preliminary findings from this study contribute to the knowledge of the appropriate distance range for consistent and high repeatability measurement of skin oxygenation.