Preparation and physiological activities of carboxymethylated derivative purified from corn bran

4th International Conference on Advanced Composite Materials and Manufacturing Engineering 2017

材料科学;化学

Zhu, Linghui^1 ; Fang, Miaoli^2 ; Ma, Jianjun^2 ; Mo, Qing^2

Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China^1

Hangzhou Medical College, Hangzhou, Zhejiang, China^2

关键词: Anti-oxidant activities;    Average molecular weight;    Chemically modified;    Degree of substitution;    Natural antioxidants;    Physiological activity;    Scavenging activities;    Water-soluble polysaccharides;   

Others  :  https://iopscience.iop.org/article/10.1088/1757-899X/207/1/012002/pdf
DOI  :  10.1088/1757-899X/207/1/012002

学科分类：材料科学（综合）

来源: IOP

【 摘 要 】

Two water-soluble polysaccharides extracted from corn bran were chemically modified to obtain their carboxymethylated derivatives (C-CBP1, C-CBP2). Theresults of degree of substitution and FT-IR analysis showed the carboxymethylation of polysaccharides were successful. The average molecular weight (Mw) of C-CBP1 and C-CBP2 were 368 and 263kDa, respectively. The degree of substitution (DS) of C-CBP1 and C-CBP2 were determined to be 0.44 and 0.46. The results showed that derivatives were effective in antioxidant and bile acidbinding activityin a dose dependent way. And C-CBP2 had the higher activity for hydroxyl radical, superoxide anion scavenging activities and bile acid capacity, as lower molecular weight plays a critical role in antioxidant activities and bile acid capacity. The results suggest that the carboxymethylated derivatives are potential natural antioxidant and blood fat reduce agent that can be used as drugs or functional food ingredients.