Characterization in vitro studies and antibacterial properties on a sol-gel derived silver incorporated bioglass

7th Maghreb Days of Material Sciences

Bouhazma, S.^1 ; Chajri, S.^1 ; Khaldi, M.^1 ; Sadiki, M.^2 ; Barkai, H.^2 ; Elabed, S.^2 ; Ibnsouda Koraichi, S.^2 ; El Bali, B.^1 ; Lachkar, M.^1

Engineering Laboratory of Organometallic and Molecular Materials (CNRST URAC19), Faculty of Sciences, University Sidi Mohamed Ben Abdellah, Po. Box 1796 (Atlas), Fez

30000, Morocco^1

Laboratory of Microbial Biotechnology, Faculty of Sciences and Technology, University Sidi Mohamed Ben Abdellah, Fez

30000, Morocco^2

关键词: Antibacterial action;    Antibacterial properties;    Culture medium;    Environmental scanning electron microscopies (ESEM);    Glass matrices;    In-vitro bioactivity;    Simulated body fluids;    Sol-gel technique;   

Others  :  https://iopscience.iop.org/article/10.1088/1757-899X/186/1/012022/pdf
DOI  :  10.1088/1757-899X/186/1/012022

来源: IOP

【 摘 要 】

The SiO2-CaO, SiO2-CaO-P2O5and SiO2-CaO-P2O5-Ag2O glass systems were synthesized by the sol-gel technique and characterized with different techniques such as X-ray diffraction (XRD), Fourier Transform Infrared spectroscopy (FTIR), and Environmental Scanning Electron Microscopy (ESEM). In vitro bioactivity tests were performed in Simulated Body Fluid (SBF). The antibacterial action of 65S5Ag (65%SiO2+ 24%CaO + 6%P2O5+ 5% Ag2O) is attributed exclusively to the leaching of Ag+ions from the glass matrix. The activity of SiO2-CaO-P2O5-Ag2O was compared with that of its binary and ternary counterpart glass system. The concentrations of Ag-bioglass, in the range of 0.05 mg/mL of culture medium, were found to inhibit the growth of these bacteria.