Operculum bone carp (cyprinus carprio sp.) scaffold is a new potential xenograft material: a preliminary study

11th Joint Conference on Chemistry in Conjunction with the 4th Regional Biomaterials Scientific Meeting

材料科学;化学;生物科学

Kartiwa, A.^1 ; Abbas, B.^2 ; Pandansari, P.^2 ; Prahasta, A.^1 ; Nandini, M.^3 ; Fadhlillah, M.^4 ; Subroto, T.^4 ; Panigoro, R.^5

Ophthalmology Department, Medical Faculty, Padjadjaran University, Bandung, Indonesia^1

National Nuclear Energy Agency of Indonesia, Jakarta

40000, Indonesia^2

Oral Surgical Department, Dentistry Faculty, Padjadjaran University, Bandung, Indonesia^3

Chemistry Department, Mathematics and Science Faculty, Padjadjaran University, Bandung, Indonesia^4

Biochemistry Department, Medical Faculty, Padjadjaran University, Bandung, Indonesia^5

关键词: Bone defect;    Large pores;    Mass ratio;    Maxillary sinus;    Orbital fracture;    Osteoblast cells;    SEM analysis;    Sem examinations;   

Others  :  https://iopscience.iop.org/article/10.1088/1757-899X/172/1/012004/pdf
DOI  :  10.1088/1757-899X/172/1/012004

来源: IOP

【 摘 要 】

Orbital floor fracture with extensive bone loss, would cause herniation of the orbital tissue into the maxillary sinus. Graft implantation should be done on the orbital fracture with extensive bone loss. Different types of grafts have their own characteristics and advantages. Xenograft has been widely studied for use in bone defects. This study was to investigate cyprinus carprio sp. opercula bone as a potential xenograft. The aim of this study was to investigate based on EDS chemical analysis using a ZAF Standardless Method of Quantitative Analysis (Oxide) and SEM examination conducted in the laboratory of Mathematics, Institute of Technology Bandung. Particularly the mass ratio of Ca and P (5.8/3:47), the result is 1.67. This is equivalent to the stoichiometric Hydroxyapatite (HA) (Aoki H, 1991, Science and medical applications of hydroxyapatite, Tokyo: Institute for Medical and Engineering, Tokyo Medical and Dental University). C N O that there is an element of protein/amino acid collagen compound, serves as a matrix together with HA. As shown in the SEM analysis that the matrix is a porous sheet-shaped (oval) that interconnect with each other, which is good scaffold. The pore is composed of large pores >200 microns and smaller pores between the large pores with a size smaller or equal to 10 microns that can serve for the attachment of osteoblast cell. In conclusion, Opercula bone carp (cyprinus carprio sp.) scaffold could be a new potential xenograft material.