Preparation and Antibacterial Activity of Inclusion Complex Sulfonatocalix[4]arene-Xanthone against Escherichia Coli

11th Joint Conference on Chemistry in Conjunction with the 4th Regional Biomaterials Scientific Meeting

材料科学;化学;生物科学

Kusumaningsih, T.^1 ; Firdaus, M.^1 ; Suparjo, H.F.^1

Department of Chemistry, Faculty of Mathematics, Natural Sciences Sebelas Maret University, Ir. Sutami street no. 36A, Kentingan, Jebres, Surakarta, Indonesia^1

关键词: Anti-bacterial activity;    Fourier transform infra red (FTIR) spectroscopy;    Inclusion complex;    Surface area;    Surface area analyzers;   

Others  :  https://iopscience.iop.org/article/10.1088/1757-899X/172/1/012059/pdf
DOI  :  10.1088/1757-899X/172/1/012059

来源: IOP

【 摘 要 】

The preparation of inclusion complex sulfonatocalix[4]arene (SC[4]A) with xanthone and measurement of antibacterial activity against Escherichia coli have been performed. Analysis of the structure of inclusion complex between SC[4]A and xanthone was investigated by using Fourier Transform Infrared Spectroscopy (FT-IR) and H Nuclear Magnetic Resonance (H-NMR). The solubility of the product in water was examined. Surface area and porous determination were analyzed by Surface Area Analyzer (SAA). Antibacterial activity test was performed for 0, 3, 6, 9, 12, and 24 hours. The results showed that antibacterial activity of the complex of xanthone SC[4]An against Escherichia coli was higher than that of xanthone it self.