Patterns of calcium oxalate monohydrate crystallization in complex biological systems

7th International Conference Radiation-thermal Effects and Processes in Inorganic Materials

材料科学;物理学

Golovanova, O.A.^1 ; Korol'Kov, V.V.^1 ; Kuimova, M.V.^2

Department of Inorganic Chemistry Omsk, F. M. Dostoevsky State University, Russia^1

National Research Tomsk Polytechnic University, Tomsk, Russia^2

关键词: Calcium oxalate monohydrate;    Calcium oxalates;    Complex biological systems;    Experimental modeling;    Hydroxyapatite crystals;    Magnesium ions;    Phase formations;    Thermodynamically stable;   

Others  :  https://iopscience.iop.org/article/10.1088/1757-899X/168/1/012062/pdf
DOI  :  10.1088/1757-899X/168/1/012062

学科分类：材料科学（综合）

来源: IOP

【 摘 要 】

The paper presents the features of calcium oxalate crystallization in the presence of additives revealed through experimental modeling. The patterns of phase formation are shown for the Ca2+- C2O42-- H2O and Ca2+- C2O42-- PO43-- H2O systems with the components and pH of the saline varying over a wide concentrations range. The effect of additives on crystallization of calcium oxalate monohydrate was investigated. It was found that the ionic strength and magnesium ions are inhibitors, and calcium oxalate and hydroxyapatite crystals are catalysts of calcium oxalate monohydrate crystallization. The basic calcium phosphate (apatite) was found to be most thermodynamically stable, which indicates its special role in kidney stone formation since it is found in virtually all stones.