Specific loss power in superparamagnetic hyperthermia: nanofluid versus composite

International Conference on Applied Sciences 2016

Osaci, M.^1 ; Cacciola, M.^2

Politehnica University of Timisoara, Department of Electrical Engineering and Industrial Informatics, 5 Revolutiei street, Hunedoara

331128, Romania^1

MediterraneaUniversity of Reggio Calabria, DICEAM, Italy^2

关键词: Biomedical applications;    Composite environment;    Composite nanoparticles;    Interaction potentials;    Linear-response theory;    Magnetic hyperthermia;    Magnetic nano-particles;    Nanoparticle geometries;   

Others  :  https://iopscience.iop.org/article/10.1088/1757-899X/163/1/012008/pdf
DOI  :  10.1088/1757-899X/163/1/012008

来源: IOP

【 摘 要 】

Currently, the magnetic hyperthermia induced by nanoparticles is of great interest in biomedical applications. In the literature, we can find a lot of models for magnetic hyperthermia, but many of them do not give importance to a significant detail, such as the geometry of nanoparticle positions in the system. Usually, a nanofluid is treated by considering random positions of the nanoparticles, geometry that is actually characteristic to the composite nanoparticles. To assess the error which is frequently made, in this paper we propose a comparative analysis between the specific loss power (SLP) in case of a nanofluid and the SLP in case of a composite with magnetic nanoparticles. We are going to use a superparamagnetic hyperthermia model based on the improved model for calculating the Néel relaxation time in a magnetic field oblique to the nanoparticle magnetic anisotropy axes, and on the improved theoretical model LRT (linear response theory) for SLP. To generate the nanoparticle geometry in the system, we are going to apply a Monte Carlo method to a nanofluid, by minimising the interaction potentials in liquid medium and, for a composite environment, a method for generating random positions of the nanoparticles in a given volume.