Structure of poly(lactic-acid) PLA nanofibers scaffolds prepared by electrospinning

The International Congress of Mechanical Engineering and Agricultural Sciences 2013

机械制造;农业科学

Gómez-Pachón, E.Y.^1 ; Vera-Graziano, R.^2 ; Campos, R Montiel^3

Escuela de Diseño Industrial, Universidad Pedagógica y Tecnológica de Colombia-UPTC, Seccional Duitama, Carrera18 Calle 22, Duitama, Boyacá, Colombia^1

Instituto de Investigaciones en Materiales, Universidad Nacional Autonoma de México, Avenida Universidad 3000, Delegation Coyoacan, 04510 Mexico, D. F., Mexico^2

Departamento de Polímeros, Universidad Autónoma Metropolitana, México, 09340 México DF, Mexico^3

关键词: Biological applications;    Nanofiber scaffold;    Polylactic acids;    Post thermal treatment;    Process condition;    Processing parameters;    Semicrystallines;    Structure property relationships;   

Others  :  https://iopscience.iop.org/article/10.1088/1757-899X/59/1/012003/pdf
DOI  :  10.1088/1757-899X/59/1/012003

学科分类：农业科学（综合）

来源: IOP

【 摘 要 】

The structural properties of poly(lactic-acid) PLA nanofiber scaffolds prepared by electrospinning have been correlated with their process condition. The influence of the electrospinning processing parameters on structure including fiber orientation, take-up velocity and post-thermal treatment was analyzed. The structure and the properties of the scaffolds were studied by x-ray diffraction (XRD), atomic force microscope (AFM), scanning electron microscopy (SEM), high resolution transmission electron microscopy (HRTEM), and differential scanning calorimetry (DSC). The existence of crystallinity into the nanofibres of PLA was found. The careful observation by HRTEM shows an amorphous core and a semicrystalline shell structure (supramolecular), and the surface of nanofiber observed by AFM shows a laminate periodic along the main axis of the fiber. These observations will be useful in understanding the structure-property relationships of oriented nanofibre scaffolds for medical or biological applications.