Energy deposition around swift proton and carbon ion tracks in biomaterials

30th International Conference on Photonic, Electronic, and Atomic Collisions

Garcia-Molina, Rafael^1 ; Dapor, Maurizio^2 ; De Vera, Pablo^3 ; Abril, Isabel^4

Departamento de Física, CIOyN, Universidad de Murcia, Murcia

E-30100, Spain^1

European Centre for Theoretical Studies in Nuclear Physics and Related Areas (ECT), Bruno Kessler Foundation, Trento Institute for Fundamental Physics and Applications (INFN-TIFPA), Trento

I-38123, Italy^2

School of Mathematics and Physics, Queen's University Belfast, Belfast

BT7 1NN, United Kingdom^3

Departament de Física Aplicada, Universitat d'Alacant, Alacant

E-03080, Spain^4

关键词: Characteristic energy;    Electron cascades;    Energy depositions;    Healthy tissues;    Malignant tumor cells;    Radial distributions;    Relative biological effectiveness;    Secondary electrons;   

Others  :  https://iopscience.iop.org/article/10.1088/1742-6596/875/12/112006/pdf
DOI  :  10.1088/1742-6596/875/12/112006

来源: IOP

【 摘 要 】

Hadron therapy is a modern cancer treatment based on the interaction of proton or heavier ion beams with living tissue, whose purpose is the destruction of the malignant tumor cells producing minimal effects on the surrounding healthy tissue. To study the physical basis of the Relative Biological Effectiveness (RBE) of different projectiles, such as protons or carbon ions, we calculate the radial distribution of energy deposited by the secondary electrons generated in biomaterials by these ions at characteristic energies around the Bragg peak. This is done by means of the simulation code SEED, which follows in detail the motion and interactions of the secondary electrons as well as the subsequent electron cascade.