INAA Application for Trace Element Determination in Biological Reference Material

International Nuclear Science and Technology Conference 2016

Atmodjo, D.P.D.^1 ; Kurniawati, S.^1 ; Lestiani, D.D.^1 ; Adventini, N.^1

Center for Applied Nuclear Sains and Technology, National Nuclear Energy Agency, Tamansari No. 71, Bandung

40132, Indonesia^1

关键词: Biological matrixes;    Biological reference materials;    Biological samples;    Coefficient of variance;    Determination methods;    Instrumental neutron activation analysis;    Standard reference material;    Trace element determination;   

Others  :  https://iopscience.iop.org/article/10.1088/1742-6596/860/1/012017/pdf
DOI  :  10.1088/1742-6596/860/1/012017

来源: IOP

【 摘 要 】

Trace element determination in biological samples is often used in the study of health and toxicology. Determination change to its essentiality and toxicity of trace element require an accurate determination method, which implies that a good Quality Control (QC) procedure should be performed. In this study, QC for trace element determination in biological samples was applied by analyzing the Standard Reference Material (SRM) Bovine muscle 8414 NIST using Instrumental Neutron Activation Analysis (INAA). Three selected trace element such as Fe, Zn, and Se were determined. Accuracy of the elements showed as %recovery and precision as %coefficient of variance (%CV). The result showed that %recovery of Fe, Zn, and Se were in the range between 99.4-107%, 92.7-103%, and 91.9-112%, respectively, whereas %CV were 2.92, 3.70, and 5.37%, respectively. These results showed that INAA method is precise and accurate for trace element determination in biological matrices.