Dosimetric comparison of DEFGEL and PAGAT formulae paired with an MRI acquisition

9th International Conference on 3D Radiation Dosimetry

Matrosic, C.^1 ; McMillan, A.^1 ; Holmes, J.^1 ; Bednarz, B.^1 ; Culberson, W.^1

University of Wisconsin, School of Medicine and Public Health, University of Wisconsin -Madison, Department of Medical Physics, Madison

WI, United States^1

关键词: Dose range;    Gel dosimeter;    MRI sequences;    Polyacrylamide gels;    Radiation-induced polymerization;    Spin echo;    Weight fractions;   

Others  :  https://iopscience.iop.org/article/10.1088/1742-6596/847/1/012012/pdf
DOI  :  10.1088/1742-6596/847/1/012012

来源: IOP

【 摘 要 】

Normoxic Polyacrylamide Gels, or nPAGs, are 3D gel dosimeters that measure dose through the process of radiation-induced polymerization. Two nPAG formulae are DEFGEL and PAGAT, which are very similar, but differ mainly due to different weight fractions of monomers. The dosimetric resolutions of the two formulae when paired with a Spin-Echo (SE) MRI sequence and a monoexponential fit were compared over a range of 0-15 Gy. It was found that in the dose range 0-6 Gy the PAGAT formula generally showed a much finer dose resolution, while the DEFGEL formula showed a finer resolution from 8-15 Gy.