Measurement of whole blood of different mammalian species in the oscillating shear field: influence of erythrocyte aggregation

2nd International Conference on Rheology and Modeling of Materials

Windberger, U.^1 ; Pöschl, Ch.^1 ; Peters, S.^1 ; Huber, J.^2 ; Van Den Hoven, R.^3

Department Biomedical Research, Medical University of Vienna, Austria^1

University Clinic for Ruminants, Kremesberg, Veterinary University Vienna, Austria^2

Clinical Unit of Equine Internal Medicine, Veterinary University Vienna, Austria^3

关键词: Erythrocyte aggregation;    Linear viscoelastic;    Physical performance;    Quasi-static conditions;    Resting heart rate;    Small-amplitude oscillations;    Species specifics;    Systematic analysis;   

Others  :  https://iopscience.iop.org/article/10.1088/1742-6596/790/1/012035/pdf
DOI  :  10.1088/1742-6596/790/1/012035

来源: IOP

【 摘 要 】

This is the first systematic analysis of mammalian blood of species with a high (horse), medium (man), and low (sheep) erythrocyte (RBC) aggregability by small amplitude oscillation technique. Amplitude and frequency sweep tests (linear viscoelastic mode) were performed with blood from healthy adult volunteers, horses, and sheep in CSS-mode. Blood samples were hematocrit (HCT) adjusted (40%, 50%, 60%) and tested at 7°C, 22°C, and 37°C. Generally, storage modulus (G) increased with HCT and decreased with temperature in each species, but the gradient of this increase was species-specific. The lower dependency of G on the equine HCT value could be a benefit during physical performance when high numbers of RBCs are released from the spleen. In sheep, an HCT-threshold had to be overcome before the desired quasi-static condition of the blood sample could be achieved, suggesting that the contact between RBCs, and between RBCs and plasma molecules must be very low. The frequencies for tests under linear viscoelastic condition were in a narrow range around the physiologic heart rate of the species. In horse, time-dependent influences concurred at frequencies lower than 3 rad.s-1probably due to sedimentation of RBC aggregates. In conclusion, blood is a fragile suspension that shows its best stability around the resting heart rate of the species.