Solvents of pus-medicines with physical-chemical aggressive action

2nd International Conference on Rheology and Modeling of Materials

Urakov, A.^1,2 ; Urakova, N.^1 ; Reshetnikov, A.^1 ; Kopylov, M.^1 ; Chernova, L.^1

Department of General and Clinical Pharmacology, Izhevsk State Medical Academy, Izhevsk, Russia^1

Department of Thermal Deformation Processes, Institute of Mechanics, Ural Branch of RAS, Izhevsk, Russia^2

关键词: Carbon dioxide under pressure;    Chemical activities;    Chemical factors;    Clinical conditions;    Homogeneous liquids;    Physical chemical property;   

Others  :  https://iopscience.iop.org/article/10.1088/1742-6596/790/1/012033/pdf
DOI  :  10.1088/1742-6596/790/1/012033

来源: IOP

【 摘 要 】

In laboratory and clinical conditions was studied rheology of pus and sulfuric tubes after their interaction with aqueous solutions of drugs from different pharmacological groups. It is shown that solutions of almost all medicines can influence or not influence on their rheology, because local action is determined not by the name, dose or route of administration of medicines. It is established that only physical-chemical properties of fluids and physical-chemical factors of their interaction with dense pus can give them the ability to dissolve or thickening pus. We found that deliberate change physical-chemical properties of medicines solutions from various pharmacological groups, namely, raising the temperature to +42°C, increasing the alkalinity above pH 8.1 and aeration as for example by introducing carbon dioxide under pressure of 0.2 ATM, or by introducing hydrogen peroxide in 0.5 - 3%, turning them into solvents of pus, ear wax and sulfuric tubes. Discovered that solutions of drugs with such physical-chemical activity may turn thick pus and solid sulfur tube in a homogeneous liquid after a few minutes after injecting them into these biological mass.