The assessment of human skin biomatrixes using raman spectroscopy method

1st International Symposium 'Physics, Engineering and Technologies for Bio-Medicine'

医药卫生;物理学;工业技术

Timchenko, E.V.^1 ; Timchenko, P.E.^1 ; Volova, L.T.^2 ; Dolgushkin, D.A.^2 ; Shalkovskaya, P.Y.^1 ; Pershutkina, S.V.^1 ; Nefedova, I.F.^2

Samara National Research University, st. Moscow highway, 34., Samara

443086, Russia^1

Institute of Experimental Medicine and Biotechnology (IEMB), Samara State Medical University, st. Gagarin, 20., Samara

443079, Russia^2

关键词: Bioimplants;    Glycosaminoglycans;    Human skin;    Optical coefficients;    Raman scattering spectroscopy;    Scattering methods;    Two-dimensional analysis;    Wave numbers;   

Others  :  https://iopscience.iop.org/article/10.1088/1742-6596/784/1/012058/pdf
DOI  :  10.1088/1742-6596/784/1/012058

来源: IOP

【 摘 要 】

There are presented the results of the analysis of the implants made of human skin by Raman scattering method. The main spectral distinctions of bioimplants by using various methods for their manufacture are shown at wavenumbers 1062 cm-1, 1645 cm-1, 1260 cm-1, 850 cm-1, 863 cm-1, corresponding to components that are important for the quality of implant: glycosaminoglycans, amide type I, amide type III, asymmetrical association C-O-S of vibration of glycosaminoglycans GAGs, tyrosine and a C-C stretching of proline ring, ribose. Has been carried out two-dimensional analysis of optical coefficients providing an opportunity to control the quality of cutaneous implants in the process of manufacturing it, and detailed analysis of Raman scattering spectroscopy.