The bioimpedance analysis of a parenchyma of a liver in the conditions of its extensive resection in experiment

1st International Symposium 'Physics, Engineering and Technologies for Bio-Medicine'

医药卫生;物理学;工业技术

Agibalov, D.Y.^1 ; Panchenkov, D.N.^2 ; Chertyuk, V.B.^3 ; Leonov, S.D.^2 ; Astakhov, D.A.^4

National Research Nuclear University, MEPhI, Moscow, Russia^1

Department of Endoscopic Surgery, SEI HPE MSMSU Them. A. I. Evdokimov, Moscow, Russia^2

Institute of Emergency Children's Surgery and Traumatology, Moscow, Russia^3

Federal Scientific Clinical Center, FMBA of Russia, Moscow, Russia^4

关键词: Bioimpedance analysis;    Complex assessment;    Experimental conditions;    Experimental justification;    Functional activities;    Morphological features;    Operational periods;    Structural feature;   

Others  :  https://iopscience.iop.org/article/10.1088/1742-6596/784/1/012048/pdf
DOI  :  10.1088/1742-6596/784/1/012048

来源: IOP

【 摘 要 】

The liver failure which is result of disharmony of functionality of a liver to requirements of an organism is the main reason for unsatisfactory results of an extensive resection of a liver. However, uniform effective criterion of definition of degree of a liver failure it isn't developed now. One of data acquisition methods about a morfo-functional condition of internals is the bioimpedance analysis (BIA) based on impedance assessment (full electric resistance) of a biological tissue. Measurements of an impedance are used in medicine and biology for the characteristic of physical properties of living tissue, studying of the changes bound to a functional state and its structural features. In experimental conditions we carried out an extensive resection of a liver on 27 white laboratory rats of the Vistar line. The comparative characteristic of data of a bioimpedansometriya in intraoperative and after the operational period with the main existing methods of assessment of a functional condition of a liver was carried out. By results of the work performed by us it is possible to claim that the bioimpedance analysis of a liver on the basis of an invasive bioimpedansometriya allows to estimate morphological features and functional activity of a liver before performance of an extensive resection of a liver. The data obtained during scientific work are experimental justification for use of an impedansometriya during complex assessment of functional reserves of a liver. Preliminary data of clinical approbation at a stage of introduction of a technique speak about rather high informational content of a bioimpedansometriya. The subsequent analysis of efficiency of the invasive bioimpedance analysis of a liver requires further accumulation of clinical data. However even at this stage the method showed the prospect for further use in clinical surgical hepathology.