Nanomaterials from bacterial cellulose for antimicrobial wound dressing

1st International Symposium 'Physics, Engineering and Technologies for Bio-Medicine'

医药卫生;物理学;工业技术

Liyaskina, E.^1 ; Revin, V.^1 ; Paramonova, E.^1 ; Nazarkina, M.^1 ; Pestov, N.^1 ; Revina, N.^1 ; Kolesnikova, S.^2

National Research Mordovia State University, Ministry of Education and Science, Saransk

430005, Russia^1

National Research Nuclear University, MEPhI (Moscow Engineering Physics Institute), Moscow

115409, Russia^2

关键词: Anti-bacterial activity;    Bio-composites;    Fusidic acid;    Gluconacetobacter;    Wound dressings;   

Others  :  https://iopscience.iop.org/article/10.1088/1742-6596/784/1/012034/pdf
DOI  :  10.1088/1742-6596/784/1/012034

来源: IOP

【 摘 要 】

Bacterial nanocellulose (BNC) is widely used in biomedical applications. BNC has attracted increasing attention as a novel wound dressing material, but it has no antimicrobial activity. To get over this problem in the present study the BNC was saturated with antibiotic fusidic acid (FA). The subject of the experiment was BNC, produced by bacteria Gluconacetobacter sucrofermentans B-11267. The resulting biocomposites have high antibiotic activity against Staphylococcus aureus and can be used in medicine as a wound dressing. The structure of BNC was analyzed by atomic force microscopy (AFM) and Fourier transform infrared spectroscopy (FTIR).