Power law relation between particle concentrations and their sizes in the blood plasma

3rd International School and Conference on Optoelectronics, Photonics, Engineering and Nanostructures (Saint Petersburg OPEN 2016)

Kirichenko, M.N.^1 ; Chaikov, L.L.^1,2 ; Zaritskii, A.R.^1

Lebedev Physical Institute, Russian Academy of Sciences, Moscow

119991, Russia^1

National Research Nuclear University MEPhI, Moscow

115409, Russia^2

关键词: Biological liquids;    Blood plasma;    Micro-particles;    Model solution;    Particle concentrations;    Power coefficients;    Power law relation;   

Others  :  https://iopscience.iop.org/article/10.1088/1742-6596/741/1/012055/pdf
DOI  :  10.1088/1742-6596/741/1/012055

来源: IOP

【 摘 要 】

This work is devoted to the investigation of sizes and concentrations of particles in blood plasma by dynamic light scattering (DLS). Blood plasma contains many different proteins and their aggregates, microparticles and vesicles. Their sizes, concentrations and shapes can give information about donor's health. Our DLS study of blood plasma reveals unexpected dependence: with increasing of the particle sizes r (from 1 nm up to 1 μm), their concentrations decrease as r-4(almost by 12 orders). We found also that such dependence was repeated for model solution of fibrinogen and thrombin with power coefficient is -3,6. We believe that this relation is a fundamental law of nature that shows interaction of proteins (and other substances) in biological liquids.