Application of nanophotosensitizers (aluminum phthalocyanine nanoparticles) for early diagnosis and prevention of inflammatory diseases

5th International Conference of Photonics and Information Optics

Kuznetsova, J.O.^1 ; Makarov, V.I.^2

National Research Nuclear University MEPhI, Moscow Engineering Physics Institute, 31Kashirskoe shosse, Moscow

115409, Russia^1

Prokhorov General Physics Institute, Russian Academy of Science, Vavilov str.38, Moscow

119991, Russia^2

关键词: Aluminum phthalocyanine;    Biological joints;    Clinical practices;    Early diagnosis;    Enamel surface;    Inflammatory disease;    Local accumulations;    Traumatology;   

Others  :  https://iopscience.iop.org/article/10.1088/1742-6596/737/1/012049/pdf
DOI  :  10.1088/1742-6596/737/1/012049

来源: IOP

【 摘 要 】

This paper deals with a possibility of new types of photosensitizers application - Aluminum Phthalocyanine nanoparticles (nAlPc) in clinical practice for diagnosis, prevention and therapy of inflammatory diseases in dentistry and traumatology. It was detected that the aluminum phthalocyanine (AlPc) fluoresces in the nanoparticle form in the presence of pathologic microflora or inflammation process. It will make possible to detect the local accumulation of pathological microflora on the enamel surface and also for diagnostics and treatment of inflammatory diseases. Experimental studies of interaction of NP-AlPc with tooth enamel and with biological joint tissue at arthrosis are presented.