A possible parameter for gait clinimetric evaluation in Parkinson's disease patients

20th Argentinean Bioengineering Society Congress

物理学;生物科学

Lescano, C.N.^1,3 ; Rodrigo, S.E.^1 ; Christian, D.A.^2

Gabinete de Tecnologia Médica, Facultad de Ingenieria, Universidad Nacional de San Juan, Argentina^1

Departamento de Matemática, Facultad de Ingenieria, Universidad Nacional de San Juan, Argentina^2

CONICET: Consejo Nacional de Investigaciones Cientificas y Técnicas, Argentina^3

关键词: Gait parameters;    Ground reaction forces;    Healthy subjects;    Parkinson disease;    Parkinson's disease;    Rating scale;    Statistically significant difference;    Vertical component;   

Others  :  https://iopscience.iop.org/article/10.1088/1742-6596/705/1/012019/pdf
DOI  :  10.1088/1742-6596/705/1/012019

学科分类：生物科学（综合）

来源: IOP

【 摘 要 】

The strength and usefulness of a rating scale for describing disease evolution relies on the accurate determination of variations representing clinically relevant changes. In this sense, the habitually used Hoehn-Yahr (HY) Scale for Parkinson Disease (PD) in its modified version distinguishes between the 2 and 2.5 stages to explain if the bilateral involvement is or is not accompanied by body balance impairment. Nevertheless, this scaling does not allow for differentiating the symptoms and signs associated with each stage accurately. Considering this difference, this work aims at analyzing some gait parameters-stance and swing phase times and magnitude of the vertical component of ground reaction force during the gait cycle-of PD patients classified as HY=2 and HY=2.5 in contrast with healthy subjects (HY=0), with the purpose of assessing whether there is a statistically significant difference among all these HY categories. For all gait parameters evaluated, the results indicated significant differences between HY=0 and HY=2.5. However, only the magnitude of the vertical component of ground reaction force presented relevant differences between HY=2 and 2.5. As expected, therefore, these results show the potential of such parameter to clinimetrically identify the level of gait impairment/disability in PD patients on the Hoehn-Yahr Scale.