Survival outcome of radioiodine therapy in post thyroidectomy thyroid carcinoma patients: Outcome of long term follow up

13th South-East Asian Congress of Medical Physics 2015

物理学;医药卫生

Haque, F.^1 ; Nahar, N.^1 ; Sultana, S.^1 ; Nasreen, F.^1 ; Jabin, Z.^1 ; Alam, A.S.M.M.^2

National Institute of Nuclear Medicine and Allied Sciences, Dhaka, Bangladesh^1

Dhaka Community Medical College and Hospital, Bangladesh^2

关键词: Best practice guidelines;    Disease free;    Long-term follow-up;    Multiple-dose;    Papillary carcinoma;    Radioiodine therapy;    Thyroid cancers;    Thyroid carcinoma;   

Others  :  https://iopscience.iop.org/article/10.1088/1742-6596/694/1/012058/pdf
DOI  :  10.1088/1742-6596/694/1/012058

学科分类：卫生学

来源: IOP

【 摘 要 】

The overall prognosis of patients with thyroid carcinoma is excellent whenever managed following best practice guidelines. Objective: To calculate sex and age group affected by thyroid cancer; to compare between single or multiple dose of radio ablation needed after thyroidectomy and to determine the percentage of patients become disease free during their follow up. Methods: This was a retrospective study done in NINMAS, Bangladesh on 687 patients from 1984 to 2004. In all cases total or near total thyroidectomy was done before commencing radioiodine therapy. Patients TG level, neck ultrasonography, thyroid scan, whole body I131scans, neck examination were done every six monthly/yearly. Results: Among 687 patients, female were more sufferers (68.1%) and female to male ratio was 2:1. Age group 19-40 years was mostly affected (57.8%). Most common type seen was papillary carcinoma (81.8%). After ablation 100 patients did not follow-up. Total 237 patients discontinued within 4 years. Remaining 450 patients undergone regular follow-up for 5 years and more, 394 were disease free (87.6%). Total recurrence of metastasis was 23 and 12 patients expired at different times. Conclusions: Long-term regular follow-up is necessary after radioiodine ablation to become free of disease.