Development of a software tool for an internal dosimetry using MIRD method

13th South-East Asian Congress of Medical Physics 2015

物理学;医药卫生

Chaichana, A.^1 ; Tocharoenchai, C.^1

Department of Radiological Technology, Faculty of Medical Technology, Mahidol University, Bangkok, Thailand^1

关键词: Absorbed dose;    Calculation process;    Development tools;    Dose calculation;    Graphic user interface;    Matlab- software;    Residence time;    Statistically significant difference;   

Others  :  https://iopscience.iop.org/article/10.1088/1742-6596/694/1/012056/pdf
DOI  :  10.1088/1742-6596/694/1/012056

学科分类：卫生学

来源: IOP

【 摘 要 】

Currently, many software packages for the internal radiation dosimetry have been developed. Many of them do not provide sufficient tools to perform all of the necessary steps from nuclear medicine image analysis for dose calculation. For this reason, we developed a CALRADDOSE software that can be performed internal dosimetry using MIRD method within a single environment. MATLAB software version 2015a was used as development tool. The calculation process of this software proceeds from collecting time-activity data from image data followed by residence time calculation and absorbed dose calculation using MIRD method. To evaluate the accuracy of this software, we calculate residence times and absorbed doses of 5 Ga- 67 studies and 5 I-131 MIBG studies and then compared the results with those obtained from OLINDA/EXM software. The results showed that the residence times and absorbed doses obtained from both software packages were not statistically significant differences. The CALRADDOSE software is a user-friendly, graphic user interface-based software for internal dosimetry. It provides fast and accurate results, which may be useful for a routine work.