Treatment planning systems for external whole brain radiation therapy: With and without MLC (multi leaf collimator) optimization

13th South-East Asian Congress of Medical Physics 2015

物理学;医药卫生

Budiyono, T.^1 ; Budi, W.S.^1 ; Hidayanto, E.^1

Department of Physics, Faculty of Science and Mathematics, Diponegoro University, Semarang

50275, Indonesia^1

关键词: Comparison result;    Conventional techniques;    External radiation fields;    Healthy tissues;    Multileaf collimators;    Target volumes;    Treatment planning systems;    Whole brain radiation therapies;   

Others  :  https://iopscience.iop.org/article/10.1088/1742-6596/694/1/012004/pdf
DOI  :  10.1088/1742-6596/694/1/012004

学科分类：卫生学

来源: IOP

【 摘 要 】

Radiation therapy for brain malignancy is done by giving a dose of radiation to a whole volume of the brain (WBRT) followed by a booster at the primary tumor with more advanced techniques. Two external radiation fields given from the right and left side. Because the shape of the head, there will be an unavoidable hotspot radiation dose of greater than 107%. This study aims to optimize planning of radiation therapy using field in field multi-leaf collimator technique. A study of 15 WBRT samples with CT slices is done by adding some segments of radiation in each field of radiation and delivering appropriate dose weighting using a TPS precise plan Elekta R 2.15. Results showed that this optimization a more homogeneous radiation on CTV target volume, lower dose in healthy tissue, and reduced hotspots in CTV target volume. Comparison results of field in field multi segmented MLC technique with standard conventional technique for WBRT are: higher average minimum dose (77.25% ± 0:47%) vs (60% ± 3:35%); lower average maximum dose (110.27% ± 0.26%) vs (114.53% ± 1.56%); lower hotspot volume (5.71% vs 27.43%); and lower dose on eye lenses (right eye: 9.52% vs 18.20%); (left eye: 8.60% vs 16.53%).