The use of innovative gadolinium-based contrast agent for MR-diagnosis of cancer in the experiment

2nd International Conference and Young Scientist School "Magnetic resonance imaging in biomedical research"

Chernov, V.^1,2 ; Medvedeva, A.^1,2 ; Sinilkin, I.^1,2 ; Zelchan, R.^1,2 ; Grigorev, E.^1 ; Frolova, I.^1 ; Nam, I.^2

Cancer Research Institute, Siberian Branch, Russian Academy of Medical Sciences, Tomsk, Russia^1

National Research Tomsk Polytechnic University, Tomsk, Russia^2

关键词: Anatomical structures;    Contrast agent;    Experimental animals;    Specific activity;    Tumor lesions;    Tumor tissues;   

Others  :  https://iopscience.iop.org/article/10.1088/1742-6596/677/1/012009/pdf
DOI  :  10.1088/1742-6596/677/1/012009

来源: IOP

【 摘 要 】

The present study of the functional suitability and specific activity of the contrast agent gadolinium-based for magnetic resonance imaging demonstrated that the investigated contrast agent intensively accumulates in organs and anatomical structures of the experimental animals. In the model of tumor lesions in animals, study have shown that investigational contrast agent accumulates in the tumor tissue and retained there in for a long enough time.