The role of encapsulated microbubbles in the diagnosis of stenosis in arteries

9th International Symposium on Cavitation

Agarwal, Karuna^1 ; Chatterjee, Dhiman^1

Department of Mechanical Engineering, Indian Institute of Technology Madras, Chennai

600036, India^1

关键词: Driving frequencies;    Micro-bubble;    Microbubbles;    Pressure amplitudes;    Sound pressure level;    Stenosed arteries;    Transmission of sounds;    Ultrasound contrast agent;   

Others  :  https://iopscience.iop.org/article/10.1088/1742-6596/656/1/012002/pdf
DOI  :  10.1088/1742-6596/656/1/012002

来源: IOP

【 摘 要 】

Numerical modelling of sound scattered by ultrasound contrast agent bubbles in arteries is presented. Nonlinear dynamics of an encapsulated microbubble coupled with transmission of sound through liquid-filled flexible tubing is developed. Based on the frequency response, a normal artery can be distinguished from that of a stenosed artery. Effects of parameters like incident pressure amplitude, driving frequency and degree of stenosis are studied. It is further found that the effect of variable pressure produced by blood flow does not have a significant effect on the observed sound pressure levels.