Design considerations for a C-shaped PET system, dedicated to small animal brain imaging, using GATE Monte Carlo simulations

International Conference on Bio-Medical Instrumentation and related Engineering and Physical Sciences

物理学;医药卫生

Efthimiou, N.^1 ; Papadimitroulas, P.^2 ; Kostou, T.^2 ; Loudos, G.^1

Department of Biomedical Engineering, Technological Educational Institute of Athens, Greece^1

Department of Medical Physics, School of Medicine, University of Patras, Greece^2

关键词: Cylindrical geometry;    Design considerations;    Geometrical phantom;    Multithreaded;    Optimum designs;    Ray-tracing technique;    Small Animal;    Spatial resolution;   

Others  :  https://iopscience.iop.org/article/10.1088/1742-6596/637/1/012005/pdf
DOI  :  10.1088/1742-6596/637/1/012005

学科分类：卫生学

来源: IOP

【 摘 要 】

Commercial clinical and preclinical PET scanners rely on the full cylindrical geometry for whole body scans as well as for dedicated organs. In this study we propose the construction of a low cost dual-head C-shaped PET system dedicated for small animal brain imaging. Monte Carlo simulation studies were performed using GATE toolkit to evaluate the optimum design in terms of sensitivity, distortions in the FOV and spatial resolution. The PET model is based on SiPMs and BGO pixelated arrays. Four different configurations with C- angle 0°, 15°, 30° and 45° within the modules, were considered. Geometrical phantoms were used for the evaluation process. STIR software, extended by an efficient multi-threaded ray tracing technique, was used for the image reconstruction. The algorithm automatically adjusts the size of the FOV according to the shape of the detector's geometry. The results showed improvement in sensitivity of ∼15% in case of 45° C-angle compared to the 0° case. The spatial resolution was found 2 mm for 45° C-angle.