会议论文详细信息
29th International Conference on Photonic, Electronic, and Atomic Collisions | |
XUV induced hydrogen migration in 5-halouracil | |
Castrovilli, M.C.^1 ; Trabattoni, A.^2 ; Bolognesi, P.^3 ; O'Keeffe, P.^3 ; Avaldi, L.^3 ; Nisoli, M.^1,2 ; Calegari, F.^1 ; Cireasa, R.^4 | |
CNR-IFN, aor2 Piazza Leonardo da Vinci 32, Milano | |
20133, Italy^1 | |
Dipartimento di Fisica, Politecnico di Milano, Milano, Italy^2 | |
CNR-ISm, Area della Ricerca di Roma 1, Monterotondo Scalo, Italy^3 | |
Institut des Sciences Moléculaires d'Orsay, UniversitéParis XI, Orsay, France^4 | |
关键词: DNA chains; Hydrogen migration; Temporal resolution; Ultra-fast; | |
Others : https://iopscience.iop.org/article/10.1088/1742-6596/635/11/112131/pdf DOI : 10.1088/1742-6596/635/11/112131 |
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来源: IOP | |
【 摘 要 】
This work presents a study of the XUV-induced ultrafast molecular dynamics of 5XU conducted with unprecedented temporal resolution. A clear dynamics occurring in 35 fs for both 5FU and 5BrU has been identified and assigned to the hydrogen migration from the C6 site to the C5 site of the molecule. Since 5XU are routinely used as radio sensitizers, the present work provides new important insights in the XUV induced structural changes responsible for the DNA breaking when these molecules are embedded in the DNA chain for radiotherapy.
【 预 览 】
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XUV induced hydrogen migration in 5-halouracil | 269KB | download |