Analysis the UV-visible Spectra of Neuroglobin Based on Two-Level Model

IWTCP-2; NCTP-39

Thao, T.T.^1 ; Anh, C.T.^1 ; Lan, N.T.^1 ; Viet, N.A.^1

Institute of Physics, Vietnam Academy of Science and Technology, 10 Dao Tan, Thu Le, Ba Dinh, Ha Noi, Viet Nam^1

关键词: Distal histidine;    Experiment data;    Heme iron;    Ligand coordination;    Neuroglobin;    Physiological functions;    Two-level models;    UV-Visible spectra;   

Others  :  https://iopscience.iop.org/article/10.1088/1742-6596/627/1/012026/pdf
DOI  :  10.1088/1742-6596/627/1/012026

来源: IOP

【 摘 要 】

Neuroglobin (Ngb), a novel member of the Globin Group, is recently discovered by Burmester et al. (2000). Its uncertain physiological function makes lots of interest. The existing of a six-coordination heme geometry with proximal and distal histidines directly creates an axis within the heme iron, while the sixth ligand coordination binds to small ligand reversibly. The analysis of UV-visible spectrum of Ngb by the well-known two-level model shows an agreement of the experiment data and theoretical results.