NMR spectroscopy of saccharide-doped PAGAT dosimeters

8th International Conference on 3D Radiation Dosimetry

Skyt, P.S.^1,2 ; Berndt, B.^1 ; Holloway, L.^1,3,4,5 ; Hill, R.^6 ; De Deene, Y.^1,7,8

Institute of Medical Physics, University of Sydney, Australia^1

Department of Medical Physics, Aarhus University Hospital, Denmark^2

Liverpool and Macarthur Cancer Therapy Centres, Ingham Institute, Australia^3

Centre for Medical Radiation Physics, University of Wollongong, Australia^4

University of New South Wales, Australia^5

Chris o'Brien Lifehouse' Sydney, Australia^6

Department of Engineering, Macquarie University, Australia^7

Department of Radiotherapy, Ghent University Hospital, Belgium^8

关键词: Chemical process;    Consumption rates;    Gel dosimeter;    Monomer concentration;    NMR spectrum;   

Others  :  https://iopscience.iop.org/article/10.1088/1742-6596/573/1/012031/pdf
DOI  :  10.1088/1742-6596/573/1/012031

来源: IOP

【 摘 要 】

The aim of this study was to investigate the chemistry of the PAGAT dosimeters when doped with saccharides and irradiated' using NMR spectroscopy. Three batches of PAGAT gel dosimeters were manufactured. Two of them were doped with 20 % glucose and sucrose' respectively. For each batch' one sample was left unirradiated while the remaining samples were irradiated to different doses. After irradiation' NMR spectra were obtained which clearly showed the composition of the dosimeter and the change in monomer concentration caused by irradiation. In addition' it revealed that the saccharides did not directly participate in the chemical process before and during irradiation but the addition of saccharides resulted in a higher consumption rate of the monomers.