Hand grips strength effect on motor function in human brain using fMRI: a pilot study

9th National Seminar on Medical Physics

物理学;医药卫生

Ismail, S.S.^1 ; Mohamad, M.^1 ; Syazarina, S.O.^2 ; Nafisah, W.Y.^3

Diagnostic Imaging and Radiotherapy Program, School of Diagnostic and Applied Health Sciences, Universiti Kebangsaan Malaysia, Kuala Lumpur

50300, Malaysia^1

Department of Radiology, Universiti Kebangsaan Malaysia Medical Center, Cheras

56000, Malaysia^2

Department of Neurology, Universiti Kebangsaan Malaysia Medical Center, Cheras

56000, Malaysia^3

关键词: Brain activation;    Computer screens;    Functional organization;    Motor activation;    Right hemispheres;    Statistical parametric mapping;    Supplementary motor areas;    Upper extremity;   

Others  :  https://iopscience.iop.org/article/10.1088/1742-6596/546/1/012005/pdf
DOI  :  10.1088/1742-6596/546/1/012005

学科分类：卫生学

来源: IOP

【 摘 要 】

Several methods of motor tasks for fMRI scanning have been evolving from simple to more complex tasks. Motor tasks on upper extremity were applied in order to excite the increscent of motor activation on contralesional and ipsilateral hemispheres in brain. The main objective of this study is to study the different conditions for motor tasks on upper extremity that affected the brain activation. Ten healthy right handed with normal vision (3 male and 7 female, age range=20-30 years, mean=24.6 years, SD=2.21) participated in this study. Prior to the scanning, participants were trained on hand grip tasks using rubber ball and pressure gauge tool outside the scanner. During fMRI session, a block design with 30-s task blocks and alternating 30-s rest periods was employed while participants viewed a computer screen via a back projection-mirror system and instructed to follow the instruction by gripping their hand with normal and strong grips using a rubber ball. Statistical Parametric mapping (SPM8) software was used to determine the brain activation. Both tasks activated the primary motor (M1), supplementary motor area (SMA), dorsal and ventral of premotor cortex area (PMA) in left hemisphere while in right hemisphere the area of primary motor (M1) somatosensory was activated. However, the comparison between both tasks revealed that the strong hand grip showed the higher activation at M1, PMA and SMA on left hemisphere and also the area of SMA on right hemisphere. Both conditions of motor tasks could provide insights the functional organization on human brain.