Two-way FSI modelling of blood flow through CCA accounting on-line medical diagnostics in hypertension

21st Fluid Mechanics Conference

物理学;力学

Czechowicz, K.^1,2 ; Badur, J.^1 ; Narkiewicz, K.^2

Energy Conversion Department, Institute of Fluid-Flow Machinery PAS-ci, Gdan´sk, Poland^1

Medical University of Gdan´sk, Gdan´sk, Poland^2

关键词: 3-D computer modeling;    Circumferential stress;    Common carotid artery;    Computational model;    Medical diagnostics;    Pathological changes;    Pressure waveforms;    Windkessel models;   

Others  :  https://iopscience.iop.org/article/10.1088/1742-6596/530/1/012011/pdf
DOI  :  10.1088/1742-6596/530/1/012011

学科分类：力学，机械学

来源: IOP

【 摘 要 】

Flow parameters can induce pathological changes in the arteries. We propose a method to asses those parameters using a 3D computer model of the flow in the Common Carotid Artery. Input data was acquired using an automatic 2D ultrasound wall tracking system. This data has been used to generate a 3D geometry of the artery. The diameter and wall thickness have been assessed individually for every patient, but the artery has been taken as a 75mm straight tube. The Young's modulus for the arterial walls was calculated using the pulse pressure, diastolic (minimal) diameter and wall thickness (IMT). Blood flow was derived from the pressure waveform using a 2-parameter Windkessel model. The blood is assumed to be non-Newtonian. The computational models were generated and calculated using commercial code. The coupling method required the use of Arbitrary Lagrangian-Euler formulation to solve Navier-Stokes and Navier-Lame equations in a moving domain. The calculations showed that the distention of the walls in the model is not significantly different from the measurements. Results from the model have been used to locate additional risk factors, such as wall shear stress or circumferential stress, that may predict adverse hypertension complications.