Common platform of Monte Carlo dose calculation on universal grid interface with Geant4 based particle therapy simulation framework

17th International Conference on the Use of Computers in Radiation Therapy

物理学;计算机科学

Iwai, G.^1 ; Takase, W.^1 ; Aso, T.^1,2 ; Watase, Y.^1 ; Sasaki, T.^1 ; Akagi, T.^3 ; Yamashita, T.^3 ; Maeda, Y.^4 ; Nishio, T.^5

Computing Research Center, High Energy Accelerator Organization, 1-1 Oho, Tsukuba, Ibaraki 305-0801, Japan^1

Department of Electrical Engineering, Nagaoka University of Technology, 1603-1 Kamitomioka, Nagaoka, Niigata 940-2188, Japan^2

Hyogo Ion Beam Medical Center, 1-2-1 Koto, Shingu-cho, Tatsuno, Hyogo 679-5165, Japan^3

Fukui Prefectural Hospital Proton Therapy Center, 2-8-1 Yotsui, Fukui, Fukui 910-8526, Japan^4

National Cancer Center Hospital East, 6-5-1 Kashiwanoha, Kashiwa, Chiba 277-8577, Japan^5

关键词: Clinical application;    Command line interface;    Distributed computing environment;    Grid computing environment;    Monte Carlo dose calculation;    Research applications;    Simulation framework;    Software applications;   

Others  :  https://iopscience.iop.org/article/10.1088/1742-6596/489/1/012001/pdf
DOI  :  10.1088/1742-6596/489/1/012001

学科分类：计算机科学（综合）

来源: IOP

【 摘 要 】

While Monte Carlo (MC) simulation is believed to be the most reliable method of dose calculation in particle therapy, the simulation time is critical in attaining sufficient statistical accuracy for clinical applications. Therefore, parallelization of simulations is essential. This paper describes a common platform of MC dose calculation in grid-distributed computing environments. The platform is flexible and effective for dose calculation in both clinical and research applications for particle therapy. The platform consists of the universal grid interface (UGI) and the Geant4-based particle therapy simulation framework (PTSIM). The UGI, written in Python, provides a command-line interface for job submission, file manipulation, and monitoring in multiple-grid middleware environments. The PTSIM is a single software application for modeling a treatment port with patient data obtained from CT images. The common platform was constructed in grid computing environments using the computing resources in five institutions. The platform utilized these resources through the NAREGI grid middleware under UGI to provide stable computing resources and a common environment for MC dose calculation in particle therapy.