Dose-response measurement in gel dosimeter using various imaging modalities

7th International Conference on 3D Radiation Dosimetry

Fujibuchi, T.^1 ; Kawamura, H.^1 ; Yamanashi, K.^1 ; Hiroki, A.^2 ; Yamashita, S.^2 ; Taguchi, M.^2 ; Sato, Y.^3 ; Mimura, K.^3 ; Ushiba, H.^3 ; Okihara, T.^3

Ibaraki Prefectural University of Health Sciences, 4669-2 Ami, Ami-machi, Inashiki-gun, Ibaraki, Japan^1

Japan Atomic Energy Agency, 1233 Watanuki, Takasahiki, Gunnma, Japan^2

Chiyoda Technol Corporation, 1-7-12, Yushima, Bunkyo-ku, Tokyo, Japan^3

关键词: Dose distributions;    Environment-friendly materials;    Fluid attenuated inversion recoveries;    Magnetic Resonance Imaging (MRI);    Measurement methods;    Polymer gel dosimeter;    Polymerization reaction;    Radiation dose distribution;   

Others  :  https://iopscience.iop.org/article/10.1088/1742-6596/444/1/012089/pdf
DOI  :  10.1088/1742-6596/444/1/012089

来源: IOP

【 摘 要 】

Measurement methods that accurately measure radiation dose distribution in a three dimensional manner in order to allow comparisons of treatment plans are needed for quality assurance. One such measurement method involves the use of a polymer gel dosimeter to measure the dose distribution in three dimensions. During irradiation, a polymerization reaction makes new chemical bonds and induces changes of the chemical structure of the gel of the gel dosimeter. In the present study, dose-response measurement of an environment-friendly material used in the gel dosimeter was performed by imaging with computed tomography (CT) and R1, R2, and fluid-attenuated inversion-recovery (FLAIR) magnetic resonance imaging (MRI) under various imaging conditions. Dose-response characteristics in the gel dosimeter used in the experiment were observed at doses of 5-20 Gy administered by X-ray CT and MRI. Although the FLAIR signal was a relative value, the dose-response values with FLAIR were excellent compared to those with R1, R2, and CT. Determination of more appropriate imaging conditions could help expand the dose-response parameters of each measurement method.