Customising PRESAGE? for diverse applications

7th International Conference on 3D Radiation Dosimetry

Juang, T.^1 ; Newton, J.^1 ; Niebanck, M.^1 ; Benning, R.^2 ; Adamovics, J.^2 ; Oldham, M.^1

Duke University Medical Center, Durham, NC, United States^1

Rider University, Lawerenceville, NJ, United States^2

关键词: Application specific requirements;    Clinical application;    Diverse applications;    Dose sensitivity;    Elastic response;    Optical clearing;    Polyurethane matrix;    Trihalomethanes;   

Others  :  https://iopscience.iop.org/article/10.1088/1742-6596/444/1/012029/pdf
DOI  :  10.1088/1742-6596/444/1/012029

来源: IOP

【 摘 要 】

PRESAGE® is a solid radiochromic dosimeter consisting of a polyurethane matrix, a triarylmethane leuco dye, and a trihalomethane initiator. Varying the composition and/or relative amounts of these constituents can affect the dose sensitivity, post-irradiation stability, and physical properties of the dosimeter. This allows customisation of PRESAGE® to meet application-specific requirements, such as low sensitivity for high dose applications, stability for remote dosimetry, optical clearing for reusability, and tissue-like elasticity for deformable dosimetry. This study evaluates five hard, non-deformable PRESAGE® formulations and six deformable PRESAGE® formulations and characterizes them for dose sensitivity and stability. Results demonstrated sensitivities in the range of 0.0029 - 0.0467 ΔOD/ (Gy·cm) for hard formulations and 0.0003 - 0.0056 ΔOD/ (Gy·cm) for deformable formulations. Exceptional stability was seen in both standard and low sensitivity non-deformable formulations, with promising applications for remote dosimetry. Deformable formulations exhibited potential for reusability with strong post-irradiation optical clearing. Tensile compression testing of the deformable formulations showed elastic response consistent with soft tissues, with further testing required for direct comparison. These results demonstrate that PRESAGE® dosimeters have the flexibility to be adapted for a wide spectrum of clinical applications.