Preparation and application of chelating multi-metal chitosan selenite

4th International Conference on Agricultural and Biological Sciences

农业科学;生物科学

Zeng, X.H.^1,2,3 ; Wu, Z.^2 ; Liu, Y.C.^2 ; Wen, S.M.^2 ; Wang, H.M.^1,2

Affiliated Dongfeng Hospital, Hubei University of Medicine, Hubei

442008, China^1

Hubei Key Laboratory of Wudang Local Chinese Medicine Research, School of Pharmacy, Hubei University of Medicine, Hubei

442000, China^2

Wudang Animal Pharmacy Co. Ltd., Hubei

442100, China^3

关键词: Agricultural fields;    Health care products;    Matching ratio;    Metal elements;    Production process;    Rare earth metal salts;    Synergistic effect;    Toxic side effects;   

Others  :  https://iopscience.iop.org/article/10.1088/1755-1315/185/1/012018/pdf
DOI  :  10.1088/1755-1315/185/1/012018

来源: IOP

【 摘 要 】

[Objective] The aim is to introduce a production processes for the preparation of chelating multi-metal chitosan selenite and its different dosage forms, which is suitable for the fields of food and feed chemistry, fertilizer chemistry or fine chemical technology, and also belongs to the field of biomedical engineering technology. [Method] Disperse chitosan in water, and stir it in water bath at 50-70°C under heating. Add trace elements and rare earth metal salts with matching ratio to make them dissolve, where ratio of chitosan and metal salts is 1:0.1-0.3 (W/W). After 2-5 hours of stirring, chitosan chelated by multi-metal can be obtained. Chelating multi-metal chitosan selenite can be made after adding selenium oxide aqueous solution. [Result] The same molecules of target products produced according to the process contain a variety of metal elements and selenium elements and have biological synergistic effect with its biological solubility and biological activity significantly improved. [Conclusion] Chelating multi-metal chitosan selenite presented in this paper is a kind of trace element and/or rare earth preparation, which is environmentally friendly, easy to absorb and rich in selenium without toxic side effects. Therefore, it could be used as a new preparation to supplement selenium and trace elements in medicine, health care products, cosmetics and agricultural fields.