Effect of drying on the porosity of the hydroxyapatite and cellulose nata de coco compositeas bone graft candidate

1st International Conference on Tropical Studies and Its Application

Anitasari, S.^1,2 ; Mu'Ti, A.^3,4 ; Hutahaean, Y.O.^5

Department of Dental Material, Dentistry Program, Faculty of Medicine, Universitas Mulawarman, East Kalimantan, Indonesia^1

Department of Microbiology, Faculty of Medicine, Universitas Mulawarman, East Kalimantan, Indonesia^2

Department of Biochemistry, Faculty of Medicine, Universitas Mulawarman, East Kalimantan, Indonesia^3

Department of Radiology, Faculty of Medicine, Universitas Mulawarman, East Kalimantan, Indonesia^4

Department of Neurology, Faculty of Medicine, Universitas Mulawarman, East Kalimantan, Indonesia^5

关键词: Bone replacement materials;    High porosity;    Hydroxyapatite (HAp);    Immersion technique;    Low compressive strengths;    Low porosity;    Osteoconductive properties;    Osteogenesis;   

Others  :  https://iopscience.iop.org/article/10.1088/1755-1315/144/1/012043/pdf
DOI  :  10.1088/1755-1315/144/1/012043

来源: IOP

【 摘 要 】

Bone graft is used to replace bone parts damaged by illness and accident. As a bone replacement material, the bone graft should be able to stimulate the process of the osteogenesis. The process of osteogenesis is influenced by the osteoconductive properties of a biomaterial, that porosity affects this process. The shells of blood scallop (Anadaragranosa) are producing hydroxyapatite (HAp),having high compressive strength, biocompatibility and osteoconductive properties, but low porosity while cellulose nata de coco (Cnc) have low compressive strength but high porosity. Therefore, the combination of two biomaterials are expected to produce composite that have high osteoconductive properties. The purpose of this research wasknowing the porosity of HAp/Cnc composite which wasbeingprecipitated for 5 hours, 15 hours, 25 hours and wasdried for 24 hours, 48 hours and 72 hours. This research usedwise drop technique to synthesis HAp powder and cellulose immersion technique for synthesis of HAp/Cnc. Results of this research, there was difference in porosity between HAp/Cnc that was precipitated for 5 hours, 15 hours and 25 hours, as well as was dried for 1 day, 2 days and 3 days. The conclusion, the synthesis of HAp/Cncwasuseful as bone graft candidate.