Antibacterial activity of cinnamon ethanol extract (cinnamomum burmannii) and its application as a mouthwash to inhibit streptococcus growth

3rd International Conference on Biological Sciences and Biotechnology

Waty, Syahdiana^1,2 ; Suryanto, Dwi^1 ; Yurnaliza^1

Department of Biology, Faculty of Mathematics and Natural Sciences, University of Sumatera Utara, Kampus USU, Jln. Bioteknologi No. 1, Medan, Indonesia^1

Medan Health Polytechnique, Ministry of Health, Jln. Jamin Ginting Km. 13.5, Lau Cih, Medan, Indonesia^2

关键词: Anti-bacterial activity;    Antibacterial compounds;    Antibacterial effects;    cinnamon bark;    mouthwash;    Secondary metabolites;    Streptococcus;    Traditional medicines;   

Others  :  https://iopscience.iop.org/article/10.1088/1755-1315/130/1/012049/pdf
DOI  :  10.1088/1755-1315/130/1/012049

来源: IOP

【 摘 要 】

Cinnamon bark has been commonly used as spicy and traditional medicine. It contains several antibacterial compounds such as flavonoids, saponins, and cinnamaldehyde. Several studies have been done to know the antibacterial effect on bacteria such as Streptococcus in vitro. This study aimed to examine the antibacterial activity of cinnamon ethanol extract against Streptococcus and its application as mouthwash to inhibit the bacteria. The cinnamon bark was macerated followed by extracted in 80% ethanol. Bacterial samples were isolated from dental plaque of patients visiting dental clinic drg. Syahdiana Waty in Medan, North Sumatra. The isolates were identified using Vitek 2 compact. Secondary metabolites were detected using previously described method. Antibacterial assay was done at extract concentration of 6.25%, 12.5%, and 25%. The result showed that alkaloids, flavonoids, saponins, and glycoside were detected in the extract. Nine bacterial species were identified as Streptococcus mitis, S. sanguinis, S. salivarius, S. pluranimalium, S. pneumoniae, S. alactolyticus, Kocuria rosea, Kocuria kristinae, and Spingomonas paucimolis. It showed that the extract of Cinnamon bark significantly inhibited Streptococcus growth, and it was effective as mouthwash.