Herbal medicine, radical scavenger and metal detoxification: bioinorganic, complexity and nano science perspectives

3rd International Conference on Biological Sciences and Biotechnology

Sumitro, Sutiman B.^1 ; Alit, Sukmaningsih^2

Laboratory of Cell, Molecular and Nano Biology, Brawijaya University, Indonesia^1

Department of Biology, Udayana University, Indonesia^2

关键词: Age-related disease;    Aromatic organic compounds;    Biological behavior;    Cardio-vascular disease;    Complex compounds;    Low molecular weight;    Metal detoxification;    Therapeutic strategy;   

Others  :  https://iopscience.iop.org/article/10.1088/1755-1315/130/1/012003/pdf
DOI  :  10.1088/1755-1315/130/1/012003

来源: IOP

【 摘 要 】

Developing Complexity Science and Nano Biological perspective giving the ideas of interfacing between modern physical and biological sciences for more comprehensive understanding of life. The study of bioinorganic is a trans-disciplinary, and will initiate the way to more comprehensive and better understanding life. We can talk about energy generation, motive forces and energy transfer at the level of macromolecules. We can then develop understanding biological behavior on nano size biological materials and its higher order using modern physics as well as thermodynamic law. This is a necessity to ovoid partial understanding of life that are not match with holism. In animal tissues, the accumulation or overwhelmed production of free radicals can damage cells and are believed to accelerate the progression of cancer, cardiovascular disease, and age-related diseases. Thus a guarded balance of radical species is imperative. Edward Kosower [1] proposed an idea of biradical in an aromatic organic compounds. Each of which having unpaired electrons. The magnetic force of this compound used for making agregation based on their magnetic characters. Bioinorganic low molecular weight complex compounds composing herbal medicine can bind toxic metals. This low molecular weight complex molecules then easily excerted the metals from the body, removing them from their either intracellular or extracellular existences. This bioinorganic chelation potential is now inspiring a new therapeutic strategies.