Awareness of antiplatelet resistance in patient with repeated episodes of thrombotic events

1st International Conference on Tropical Medicine and Infectious Diseases (ICTROMI) Faculty of Medicine Universitas Sumatera Utara

Dalimunthe, N.N.^1,2 ; Hamonangan, R.^1 ; Antono, D.^1 ; Prasetya, I.^1 ; Rusdi, L.^1

Division of Cardiology, Department of Internal Medicine, Faculty of Medicine, University Indonesia, Jl. Diponegoro No. 71, Jakarta

10430, Indonesia^1

Division of Cardiovascular, Departmetint of Internal Medicine, Faculty of Medicine, Universitas Sumatera Utara, Jl. dr. T Mansyur No. 5, Medan

20154, Indonesia^2

关键词: Acute coronary syndromes;    Cardiovascular event;    Clopidogrel;    Coronary bypass;    Follow up;    Function tests;    Platelet response;    Recurrent events;   

Others  :  https://iopscience.iop.org/article/10.1088/1755-1315/125/1/012121/pdf
DOI  :  10.1088/1755-1315/125/1/012121

来源: IOP

【 摘 要 】

Antiplatelet has been the cornerstones management of acute coronary syndrome. However, numbers of patients on these agents had episodes of adverse cardiovascular events. A 65-year-old woman post cardiac coronary bypass surgery on dual antiplatelet therapy, Aspirin, and Clopidogrel underwent several episodes of thrombotic events despite good adhered to thedailyantiplatelet regimen.These recurrent events had led to clinical suspicious of antiplatelet resistance. Platelet function test was performed which indicates a poor platelet response to Clopidogrel. Clopidogrelwas discontinued and Ticagrelor was prescribed together with Aspirin. During two months of follow up, there is no episode of chest discomfort.