Vancomycin-resistant Staphylococcus aureus (VRSA) in hepatic cirrhosis patient: a case report

1st International Conference on Tropical Medicine and Infectious Diseases (ICTROMI) Faculty of Medicine Universitas Sumatera Utara

Ramazoni, M.^1 ; Siregar, M.L.^2 ; Jamil, K.F.^2

Internal Medicine Resident, Syiah Kuala University Medical School, Banda Aceh, Indonesia^1

Department of Internal Medicine, Division of Tropical and Infectious Diseases, Syiah Kuala University Medical School, Dr.Zainoel Abidin Hospital, Banda Aceh

23126, Indonesia^2

关键词: Distribution chains;    Gastrointestinal bleeding;    Hepatic cirrhosis;    Methicillin-resistant staphylococcus aureus;    Microbiological cultures;    Minimum inhibitory concentration;    Resistant Staphylococcus aureus;    Trimethoprim;   

Others  :  https://iopscience.iop.org/article/10.1088/1755-1315/125/1/012096/pdf
DOI  :  10.1088/1755-1315/125/1/012096

来源: IOP

【 摘 要 】

The irrational use of vancomycin in methicillin-resistant Staphylococcus aureus (MRSA) infections result in the emergence of vancomycin-resistant Staphylococcus aureus (VRSA) pathogen, which can pose a threat to the world healthcare. A 32-year-old male with hepatic cirrhosis patient admitted with recurrent gastrointestinal bleeding with a wound in his left leg since 6 months ago; the result microbiological culture showed a VRSA with minimum inhibitory concentration (MIC) vancomycin ≥32μg/mL The patient was treated with trimethoprim/sulfamethoxazole combination according to cultural sensitivity. The second microbiological culture showed thesame result. VRSA is a rare and difficult condition to handle. The success of therapy for this VRSA case warn us how important to cut the S. aureus distribution chain with a high level of resistance.