Management of tetanus complication

1st International Conference on Tropical Medicine and Infectious Diseases (ICTROMI) Faculty of Medicine Universitas Sumatera Utara

Somia, I.K.A.^1

Division of Tropical and Infectious Disease, Department of Internal Medicine, Faculty of Medicine, Sanglah General Hospital, Udayana University, Bali, Indonesia^1

关键词: Critical care;    Intensive care;    Long term care;    Management goals;    Mortality rate;    Muscle spasms;    Toxin production;   

Others  :  https://iopscience.iop.org/article/10.1088/1755-1315/125/1/012086/pdf
DOI  :  10.1088/1755-1315/125/1/012086

来源: IOP

【 摘 要 】

The mortality rate of tetanus is still high; it is because of various complications due to muscle spasms, autonomic dysfunction, as well as due to prolonged critical care. Management of tetanus with its complications is in intensive care facilities. Management goals include stopping toxin production, neutralization of unbound toxin, management of the airway, muscle spasm control, treatment of autonomic dysfunction and general supportive management. Currently, diazepam is still an effective medication to control of muscle spasm and rigidity. Therapy for autonomic dysfunction that supported by evidence is MgSO4. Also, general supportive management for long-term care remains necessary to prevent other complications such as thromboembolism, infection, malnutrition, and others.