The comparative accuracy of rapid diagnostic test with microscopy to diagnose malaria in subdistrict lima puluh batubara regency North Sumatera province

1st International Conference on Tropical Medicine and Infectious Diseases (ICTROMI) Faculty of Medicine Universitas Sumatera Utara

Rezeki, S.^1,2 ; Pasaribu, A.P.^3,4

Postgraduate Program in Tropical and Health Medicine, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia^1

Department of Parasitology, Faculty of Medicine, Universitas Syiah Kuala, Banda Aceh, Indonesia^2

Departement of Child Health, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia^3

Clinical Research Unit, Universitas Sumatera Utara Hospital, Medan, Indonesia^4

关键词: Diagnostic tests;    Laboratory skills;    Likelihood ratios;    Malaria diagnosis;    Microscopic methods;    Negative predictive value;    Positive predictive values;    Skill requirements;   

Others  :  https://iopscience.iop.org/article/10.1088/1755-1315/125/1/012020/pdf
DOI  :  10.1088/1755-1315/125/1/012020

来源: IOP

【 摘 要 】

Indonesia is the country where malaria is still the most common population problem. The high rate of mortality and morbidity occurred due to delays in diagnosis whichis strongly influenced by the availability of diagnostic tools and personnel with required laboratory skill. This diagnostic study aims to compare the accuracy of a Rapid Diagnostic Test (RDT) without skill requirement, to agold standard microscopic method for malaria diagnosis. The study was conducted in Subdistrict Lima Puluh North Sumatera Province from December 2015 to January 2016. The subject was taken cross-sectionally from a population with characteristics typically found in malaria patients in Subdistrict Lima Puluh. The result showed a sensitivity of 100% and a specificity of 72.4% with a positive predictive value of 89.9% and a negative predictive value of 100%; the negative likelihood ratio is 0 and the positive likelihood ratio of 27.6 for Parascreen. This research indicates that Parascreen had a high sensitivity and specificity and may be consideredas an alternative for the diagnosis of malaria in Subdistrict Lima Puluh North Sumatera Province especially in areas where no skilled microscopist is available.