Transmission of porcine circovirus genotype type 2 (PCV2) in Russia and genotype association (PCV2d) with porcine dermatitis and nephropathy syndrome (PDNS)

International Scientific Conference «AGRITECH-2019: Agribusiness, Environmental Engineering and Biotechnologies»

农业科学;生态环境科学;生物科学

Raev, S.A.^1 ; Yuzhakov, A.G.^1 ; Alekseev, K.P.^1 ; Kostina, L.V.^1 ; Gulyukin, M.I.^1 ; Stepanova, T.V.^1 ; Zaberezhniy, A.D.^1 ; Aliper, T.I.^1

Federal State Budget Institution Federal Scientific Center VIEV, 24-1, Ryazanskiy pr., Moscow

109428, Russia^1

关键词: Clinical manifestation;    Different ages;    Enzyme linked immunosorbent assay;    Field observations;    Immune response;    Nephropathy;    Pig farms;    Russian federation;   

Others  :  https://iopscience.iop.org/article/10.1088/1755-1315/315/4/042026/pdf
DOI  :  10.1088/1755-1315/315/4/042026

来源: IOP

【 摘 要 】

The study of the prevalence of PCV2 genotypes in pig farms of the Russian Federation is presented. It is shown that currently the genotype PCV2d is the most common, which is important in connection with the assumed probability of lack of the immune response to PCV-2d induced by PCV-2a-based vaccines. The main goal of this investigation was to conduct monitoring studies for DNA, immunoglobulins IgG and IgM classes to PCV2 by the polymerase chain reaction (PCR) and enzyme-linked immunosorbent assay (ELISA) assays, respectively, as well as identification of the PCV2 genotype by sequencing of pigs of different ages were carried out at one of the Russian industrial pig farms with PCVAD (Porcine circovirus associated disease) outbreaks that used PCV2a vaccination. The data of this field observation indicates that PCV2d - is a major genotype in Russia. Additionally, it was shown that PCV2d prevalence in the farm correlates with clinical manifestation of PCVAD.